Synthesis and Reactions of Quinoxaline Derivatives
نویسندگان
چکیده
منابع مشابه
Synthesis of tetrazolo [1,5-a]quinoxaline derivatives
Displacement reaction of 2,3-dichloroquinoxaline with secondary amines in boiling ethanol afforded it`s mono aminoquinoxaline derivatives. Further reaction of the latter compounds with sodium azide in warm dimethylsulfoxide achieved a group of 4-amino tetrazolo[1,5-a]quinoxaline derivatives. 1HNMR spectra of these compounds are discussed.
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The high commercial demand for quinoxalines needs a rapid, greener and safer synthetic method among the chemists. A series of quinoxaline derivatives has been synthesized by condensation of diamines and dicarboniles in microwave heating conditions and in solvent free media. This environmentally benign synthetic approach gives us excellent yields (80-90%) in shorter reaction time (3.5 minutes.)....
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Stable derivatives of oxaphosphaphenanthrenes were prepared using multicomponent reactions of 3-bromo-2-naphthol, dialkyl acetylenedicarboxylate and trimethyl or triphenyl phosphite under microwave conditions with good yields.
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2-Chloro-3-methylquinoxaline was selected as a nucleus around which various molecular transformations were performed to obtain new compounds expected to possess optimized antimicrobial activity. As very little work regarding attachment of ether linkages replacing chlorine at C-2 has been reported, it was thought worthwhile to synthesize various quinoxaline derivatives by replacing the C₂ chlori...
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SR protein-specific kinase-1 (SRPK-1) has been identified as a validated target for hepatitis B virus (HBV). A series of novel tricyclic quinoxaline derivatives was designed and synthesised as potential kinase inhibitory antiviral agents and was found to be active and selective for SRPK-1 kinase. Most of these novel compounds have drug-like properties according to experimentally determined LogP...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1984
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.57.1653